Genetic and epigenetic insights into fetal alcohol spectrum disorders
نویسندگان
چکیده
منابع مشابه
Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms
Fetal alcohol spectrum disorders (FASD) are a group of related conditions that arise from prenatal exposure to maternal consumption of the teratogen, ethanol. It has been estimated that roughly 1% of children in the US suffer from FASD (Sampson etal., 1997), though in some world populations, such as inhabitants of some poorer regions of South Africa, the rate can climb to as high as 20% (May et...
متن کاملFetal Alcohol Spectrum Disorders.
Prenatal exposure to alcohol can damage the developing fetus and is the leading preventable cause of birth defects and intellectual and neurodevelopmental disabilities. In 1973, fetal alcohol syndrome was first described as a specific cluster of birth defects resulting from alcohol exposure in utero. Subsequently, research unequivocally revealed that prenatal alcohol exposure causes a broad ran...
متن کاملFetal Alcohol Spectrum Disorders
Forty years ago, alcohol was not commonly recognized as a teratogen, an agent that can disrupt the development of a fetus. Today, we understand that prenatal alcohol exposure induces a variety of adverse effects on physical, neurological, and behavioral development. Research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) has contributed to the identification of the ...
متن کاملFetal alCoHol sPeCtruM disorders
Objective: To conduct a combined analysis of the estimated effects of maternal average weekly alcohol consumption, and any binge drinking, in early to mid pregnancy on general intelligence, attention, and executive function in 5-year-old children. Design: Follow-up study. Setting: Neuropsychological testing in four Danish cities 2003–2008. Population: A cohort of 1628 women and their children s...
متن کاملFetal Alcohol Spectrum Disorders (fasd)
Establishing a unique neurobehavioural profile for people exposed to alcohol in utero would be a tremendous aid in diagnosis, treatment planning and epidemiological research. Epidemiological studies of fetal alcohol syndrome have shown that only one?third of the babies born to mothers who drank heavily during pregnancy presented with full-blown FAS. 2 Moreover, the majority of people who were e...
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ژورنال
عنوان ژورنال: Genome Medicine
سال: 2010
ISSN: 1756-994X
DOI: 10.1186/gm148